EU: Context Sensitive Multisensory Object Recognition (HBP)
At a glance
Project duration
04/2016
– 03/2018
Project description
The central hypothesis or this task is that pyramidal neurons throughout the cortex act as associative elements, linking external feed-forward information about the outside world with internal feedback predictions from the brains internal representation. Objective: is to determine how feedback interacts with perceptual behaviour, using stimulation (optical and/or electrical) of single cells or small populations of neurons in a primary sensory region while imaging the effect of feedback input from perirhinal cortex on large scale population imaging throughout a cortical column. Methods: We will train animals in a licking task, where perception of single cell stimulation or microstimulation in somatosensory cortex is perceived by the animal. The effect of long range inputs on the animals’ ability to detect intracortical stimulation will be measured with optogenetic stimulation of the inputs. The effect of microstimulation and single cell stimulation on cortico-cortical circuit activation will be measured by imaging calcium signals through implanted microprisms with 2-photon imaging throughout a cortical column. The interaction between perirhinal optogenetic activation, effect on licking behaviour and on the local circuit activation will be measured. Does activation or inactivation of feedback inputs to somatosensory cortex, affect when or whether the animal licks? Does the activation or inactivation of feedback inputs affect the number of neurons activated in cortical column by the microstimulus.
Cooperation partners
- Cooperation partnerUniversityFinland
Aalto University
- Cooperation partnerUniversityGreece
Athens University of Economics and Business - Research Center
- Cooperation partnerUniversitySpain
Autonomous University of Madrid
- Cooperation partnerSpain
Barcelona Supercomputing Center - Centro Nacional de Supercomputation
- Cooperation partnerUniversityGermany
Bauhaus University, Weimar
- Cooperation partnerUniversityGermany
Bielefeld University
- Cooperation partnerIsrael
Bloomfield Science Museum Jerusalem
- Cooperation partnerUniversityGreat Britain
Cardiff University
- Cooperation partnerUniversityFrance
Claude Bernard Lyon 1 is a university
- Cooperation partnerSpain
Consorci Institut d'Investigacions Biomediques August Pi i Sunyer
- Cooperation partnerItaly
Consorzio Interuniversitario Cineca
- Cooperation partnerPortugal
D. Anna de Sommer Champalimaud and Dr. Carlos Montez Champalimaud Foundation
- Cooperation partnerUniversityGreat Britain
De Montfort University
- Cooperation partnerUniversityGermany
Dresden University of Technology
- Cooperation partnerNetherlands
Dutch national research institute for mathematics and computer science
- Cooperation partnerUniversitySwitzerland
Ecole Polytechnique federale de Lausanne
- Cooperation partnerNon-university research institutionItaly
European Brain Research Institute Rita Levi-Montalcini
- Cooperation partnerUniversityItaly
European LAboratory for Non-Linear spectroscopy
- Cooperation partnerDenmark
Fonden Teknologiradet
- Cooperation partnerGermany
Fortiss GmbH
- Cooperation partnerNon-university research institutionGermany
Fraunhofer Society for the Advancement of Applied Research
- Cooperation partnerNon-university research institutionFrance
French Alternative Energies and Atomic Energy Commission
- Cooperation partnerFrance
French National Center for Scientific Research
- Cooperation partnerNon-university research institutionGermany
German Center for Neurodegenerative Diseases
- Cooperation partnerUniversityBelgium
Ghent University
- Cooperation partnerUniversityGermany
Goethe University Frankfurt
- Cooperation partnerUniversityAustria
Graz University of Technology
- Cooperation partnerUniversityIsrael
Hebrew University of Jerusalem
- Cooperation partnerNon-university research institutionGermany
Heidelberg Institute for Theoretical Studies HITS gGmbH
- Cooperation partnerUniversityGermany
Heidelberg University
- Cooperation partnerUniversityGreat Britain
Imperial College of Science, Technology and Medicine
- Cooperation partnerSlovenia
Institut Jozef Stefan
- Cooperation partnerFrance
Institut National de Recherche Eninformatique et Automatique
- Cooperation partnerFrance
Institut Pasteur
- Cooperation partnerNon-university research institutionSwitzerland
Institut Suisse de Bioinformatiquefondation ISB
- Cooperation partnerFrance
Institut du Cerveau et de la Moelle Epiniere
- Cooperation partnerSpain
Institute for Bioengineering of Catalonia
- Cooperation partnerHungary
Institute of Experimental Medicine - Hungarian Academy of Sciences
- Cooperation partnerAustria
Institute of Science and Technology Austria
- Cooperation partnerNon-university research institutionGermany
Jülich Research Centre
- Cooperation partnerUniversityGermany
Karlsruhe Institute of Technology
- Cooperation partnerSweden
Karolinska Institutet
- Cooperation partnerUniversityBelgium
Katholieke Universiteit Leuven
- Cooperation partnerUniversityGreat Britain
King's College London
- Cooperation partnerUniversitySweden
Kunglia Tekniska Hoegskolan
- Cooperation partnerUniversitySwitzerland
Lausanne University Hospital
- Cooperation partnerUniversityNetherlands
Leiden University Medical Center
- Cooperation partnerUniversitySweden
Linnaeus University
- Cooperation partnerUniversityNetherlands
Maastricht University
- Cooperation partnerNon-university research institutionGreat Britain
Medical Research Council
- Cooperation partnerUniversityAustria
Medical University of Innsbruck
- Cooperation partnerUniversityGreat Britain
Middlesex University Higher Education Corporation
- Cooperation partnerNon-university research institutionItaly
National Institute for Nuclear Physics
- Cooperation partnerItaly
National Research Council (Italy)
- Cooperation partnerUniversityGreece
National and Kapodistrian University of Athens
- Cooperation partnerUniversityNorway
Norwegian University of Life science
- Cooperation partnerUniversityFrance
Pierre and Marie Curie University
- Cooperation partnerUniversityItaly
Politecnico di Torino
- Cooperation partnerUniversitySpain
Polytechnic University of Madrid
- Cooperation partnerUniversityGermany
RWTH Aachen University
- Cooperation partnerUniversityNetherlands
Radboud University
- Cooperation partnerUniversityTurkey
Sabanci University
- Cooperation partnerUniversityItaly
Sant'Anna School of Advanced Studies -Pisa
- Cooperation partnerUniversityItaly
Scuola Normale Superiore
- Cooperation partnerUniversitySwitzerland
Swiss Federal Institute of Technology in Zurich
- Cooperation partnerUniversityFinland
TTY-Saatio
- Cooperation partnerUniversityGermany
Technical University of Darmstadt
- Cooperation partnerUniversityDenmark
Technical University of Denmark
- Cooperation partnerUniversityGermany
Technical University of Munich
- Cooperation partnerUniversityIsrael
Tel Aviv University
- Cooperation partnerUniversityGreat Britain
The Chancellor, Masters and Scholars of the University of Oxford
- Cooperation partnerGermany
The FZI Research Center for Information Technology
- Cooperation partnerItaly
The Istituto Superiore di Sanità
- Cooperation partnerUniversityGreece
The Research Committee of the Technical University of Crete
- Cooperation partnerNon-university research institutionNetherlands
The Royal Netherlands Academy of Arts and Sciences
- Cooperation partnerUniversityGreat Britain
The University Court of the University of Aberdeen
- Cooperation partnerUniversitySpain
The University of Castilla-La Mancha
- Cooperation partnerUniversityGreat Britain
The University of Manchester
- Cooperation partnerUniversityItaly
Univeristy of Milan
- Cooperation partnerUniversitySpain
Universidad Pompeu Fabra
- Cooperation partnerUniversitySpain
Universidad Rey Juan Carlos
- Cooperation partnerUniversityFrance
Universite d' Aix Marseille
- Cooperation partnerUniversityGreat Britain
University College London
- Cooperation partnerUniversityGermany
University Hospital Aachen
- Cooperation partnerGermany
University Medical Center Hamburg-Eppendorf
- Cooperation partnerUniversityNetherlands
University of Amsterdam
- Cooperation partnerUniversityBelgium
University of Antwerp
- Cooperation partnerUniversitySpain
University of Barcelona
- Cooperation partnerUniversitySwitzerland
University of Basel
- Cooperation partnerUniversitySwitzerland
University of Bern
- Cooperation partnerUniversityFrance
University of Bordeaux
- Cooperation partnerUniversityHungary
University of Debrecen
- Cooperation partnerUniversityGermany
University of Düsseldorf
- Cooperation partnerUniversityGreat Britain
University of Edinburgh
- Cooperation partnerUniversitySwitzerland
University of Geneva
- Cooperation partnerUniversityGreat Britain
University of Glasgow
- Cooperation partnerUniversitySpain
University of Granada
- Cooperation partnerUniversityGermany
University of Hamburg
- Cooperation partnerUniversityFinland
University of Helsinki
- Cooperation partnerUniversityGreat Britain
University of Leeds
- Cooperation partnerUniversityBelgium
University of Liège
- Cooperation partnerUniversityPortugal
University of Minho
- Cooperation partnerUniversityNorway
University of Oslo
- Cooperation partnerUniversityItaly
University of Pavia - Universita Degli Studi di Pavia
- Cooperation partnerUniversityGreat Britain
University of Sheffield
- Cooperation partnerUniversityGreat Britain
University of Surrey
- Cooperation partnerUniversityGreat Britain
University of Sussex
- Cooperation partnerUniversityGermany
University of Wuppertal
- Cooperation partnerUniversitySwitzerland
University of Zurich
- Cooperation partnerUniversityGreat Britain
University of the West of England, Bristol
- Cooperation partnerUniversitySweden
Uppsala University
- Cooperation partnerUniversityNetherlands
Vrije University Amsterdam
- Cooperation partnerResearch instituteIsrael
Weizmann Institute of Science
- Cooperation partnerUniversityFrance
École normale supérieure
- Cooperation partnerAustria
Österreichische Studiengesellschaft für Kybernetik