GRK 754: Myokardiale Genexpression und Funktion - Myokardhypertrophie
Heart failure represents one of the most prominent cardiac problems of all western societies. In most cases it is preceded by myocardial hypertrophy. The research aim of the graduate course is to elucidate the physiological, biochemical and genetic mechanisms that lead to myocardial hypertrophy and its transition into cardiac failure. Better understanding of these mechanisms will create new therapeutic options. The research program is characterized by four closely combined main focuses: I: Animal Models of Hypertrophy; II: Functional Genomics and Proteomics; III: Specific Molecular Mechanisms; IV: Clinical Aspects. The scientific education focuses on the interdisciplinary training of biochemists, biologists and other theoretical scientists together with medical doctors and students.
Beteiligte Fakultäten/Institute der Humboldt-Universität zu Berlin:
German Heart Institute Berlin, in cooperation with the following departments of Humboldt-Universität Berlin: Medical Faculty Charité; Biomedical Research Centre; Dept of Internal Medicine, Cardiology and Franz Volhard Clinic; Institute for Human Genetics; Institute for Pharmacology and Toxicology; Institute for Physiology; Dept of Nephrology.
Weitere beteiligte Einrichtungen:
Free University zu Berlin: Dept of Clinical Pharmacology and
Toxicology.
Sprecher:
Prof. Dr. Vera Regitz-Zagrosek
Deutsches Herzzentrum Berlin
Klinik für Innere Medizin - Kardiologie
Augustenburger Platz 1
D-13353 Berlin
Tel.: +49 (030) 4593-2410, 2230
Fax.: +49 (030) 4953-2409
e-mail: vrz@dhzb.de
Laufzeit:
10/2001 - 03/2006