Collaborative Research Centres at Humboldt-Universität Berlin - Completed Projects
CRC 273: Hyperthermia: clinical aspects and methodology
Spokesperson:
Prof. Dr. Dr. h.c. Roland Felix
Charité - Universitätsmedizin Berlin
Clinic of Radiation Therapy
Augustenburger Platz 1
D-13353 Berlin
Phone: +49 30 450-528071/-528132
Fax: +49 30 450-528921
E-Mail: p-m.kloetzel@charite.de
Duration: 01/99 - 12/07
CRC 373: Quantification and simulation of economic processes
Spokesperson:
Prof. Dr. Wolfgang Härdle
Faculty of Economics and Business Administration
Section of Statistics
Spandauer Str. 1
D-10178 Berlin
Phone: +49 30 2093-5631
Fax: +49 30 2093-5649
E-Mail: haerdle@wiwi.hu-berlin.de oder sfb373@wiwi.hu-berlin.de
Duration: 01/94 - 12/02
CRC 421: Protective and pathological effects of antigen processing
Spokesperson:
Prof. Dr. Peter-Michael Kloetzel
Charité - Universitätsmedizin Berlin
Department of Biochemistry
Monbijoustr. 2
D-10117 Berlin
Phone: +49 30 450-528071/-528132
Fax: +49 30 450-528921
E-Mail: p-m.kloetzel@charite.de
Duration: 01/99 - 12/08
CRC 429: Molecular physiology, energetics, and regulation of primary metabolism in plants
Spokesperson:
Prof. Dr. rer. nat. Thomas Börner
Faculty of Life Sciences
Department of Biology
Chausseestr. 117
D-10015 Berlin
Phone: +49 30 2093-8142
Fax: +49 30 2093-8141
E-Mail: thomas.boerner@rz.hu-berlin.de
Duration: 01/99 - 12/10
CRC 448: Mesoscopically organized composites
Spokesperson:
Prof. Dr. Jürgen P. Rabe (since 1.1.2004)
Faculty of Mathematics and Natural Sciences
Department of Physics
Newtonstr. 15
D-12489 Berlin
Phone: +49 30 2093-7788
Fax: +49 30 2093-7632
E-Mail: rabe@physik.hu-berlin.de
Duration: 01/98 - 12/09
CRC 507: The Significance Of Non-Neuronal Cells For Neurological Diseases
Spokesperson:
Prof. Dr. Karl M. Einhäupl
Charité - Universitätsmedizin Berlin
Clinic of Neurology
Schumannstr. 20-21
D-10098 Berlin
Phone: +49 30 450-560102
Fax: +49 30 450-560932
E-Mail: karl.einhaeupl@charite.de
Duration: 07/95 - 12/07
CRC 546: Structure, dynamics and reactivity of aggregates of transition metal oxides
Spokesperson:
Prof. Dr. rer. nat. Joachim Sauer
Faculty of Mathematics and Natural Sciences
Department of Chemistry
Brook-Taylor-Str. 2
D-12489 Berlin
Phone: +49 30 2093-7135
Fax: +49 30 2093-7136
E-Mail: js@chemie.hu-berlin.de
Duration: 07/99 - 06/11
CRC 555: Complex nonlinear processes
Spokesperson:
Prof. Dr. Lutz Schimansky-Geier
Faculty of Mathematics and Natural Sciences
Department of Physics
Newtonstr. 15
D-12489 Berlin
Phone: +49 30 2093-7624
Fax: +49 30 2093-7638
E-Mail: lutz.schimansky-geier@physik.hu-berlin.de
Duration: 07/98 - 06/10
CRC 577: Molecular basis of clinical variability in Mendelian disorders
Spokesperson:
Prof. Dr. Karl Sperling
Charité - Universitätsmedizin Berlin
Department of Human Genetics
Augustenburger Platz 1
D-13353 Berlin
Phone: +49 30 450-566052
Fax: +49 30 450-566904
E-Mail: karl.sperling@charite.de
Duration: 07/01 - 09/09
CRC 618: Theoretical biology: robustness, modularity and evolutionary design of living systems
Experimenters and theoreticians jointly investigate the structural properties of cellular signal routes, regulatory and neuronal networks as well as the susceptibility of such networks to parasitic manipulations. The investigations aim to develop theoretical concepts, mathematical models and methods which can benefit biologists and physicians.
Spokesperson:
Prof. Dr. rer. nat. Peter Hammerstein
Faculty of Life Sciences
Department of Biology
Invalidenstr. 43
D-10115 Berlin
Phone: +49 30 2093-9102
Fax: +49 30 2093-8801
E-Mail: p.hammerstein@biologie.hu-berlin.de
Duration: 07/02 - 06/13
CRC 640: Representations of social order - intercultural and inter-temporary comparisons
The researchers involved consider the representations of different social orders to be forms of knowledge. They investigate the exchange of representations in order to understand how social orders emerge, develop and change. A total of 26 Asian, African and Latin American countries are dealt with in the framework of the research project.
Spokesperson:
Prof. Dr. Jörg Baberowski
Faculty of Arts and Humanities I
Department of History
Mohrenstraße 40-41
D-10099 Berlin
Phone: +49 30 2093-4862
Fax: +49 30 2093-4893
E-Mail: BaberowskiJ@geschichte.hu-berlin.de
Duration: 07/04 - 12/13
CRC 644: Transformations of antiquity
Research into the subject aims to find out in which way and to what extent art and science of antiquity was taken over and changed in subsequent epochs. It covers architecture and technology, literature, the human body and general knowledge in the course of the gradual formation of science and culture of western societies from the end of antiquity up to the present time.
Spokesperson:
Prof. Dr. Johannes Helmrath
Faculty of Arts and Humanities I
Department of History
Section of Cultural Studies
Friedrichstraße 191-193
D-10117 Berlin
Phone: +49 30 2093-705538
Fax: +49 30 2093-70646
E-Mail: helmrathj@geschichte.hu-berlin.de
Duration: 01/05 - 12/16
Homepage: http://www.sfb-antike.de/
CRC 647: Space - time - matter: analytic and geometric structures
The projects dealt with can be divided into two major groups: group A investigates the geometry of matter, and group B is concerned with the evolution of geometric structures. Each group deals with five projects with both mathematicians and physicists contributing to the solution of interdisciplinary problems.
Spokesperson:
Prof. Dr. Matthias Staudacher
Faculty of Mathematics and Natural Sciences
Department of Physics / Mathematics
Zum Großen Windkanal 6
D-12489 Berlin
Phone: +49 30 2093-66392
Fax: +49 30 2093-66391
E-Mail: matthias@mathematik.hu-berlin.de
Duration: 01/05 - 12/16
Homepage: http://www.raumzeitmaterie.de/
CRC 649: Economic risk
Researchers investigate fundamental economic risks and their consquences. The distribution and control of risks is being dealt with in three project groups.
Spokesperson:
Prof. Wolfgang Härdle, Ph.D.
Faculty of Economics and Business Administration
Economic Policy
Spandauer Str. 1
D-10178 Berlin
Phone: +49 30 2093-5708
Fax: +49 30 2093-5617
E-Mail: uhlig@wiwi.hu-berlin.de
Duration: 01/05 - 12/16
Homepage: http://sfb649.wiwi.hu-berlin.de/
CRC 650: Cellular approaches to a suppression of unwanted immune reactions - from bench to bedside
The researchers involved in the project aim to find new conceptions for the therapy of diseases caused by unwanted immune reactions such as autoimmune diseases, allergies and transplant rejection. Up until now only unspecific immunosuppressive medications are available. Their effectiveness is limited, their side-effects considerable. They need to be administered over a long period of time and are, therefore, very expensive.
Spokesperson:
Prof. Dr. rer. nat. Alf Hamann
Charité - Universitätsmedizin Berlin
Internal Medicine Clinic Specializing in Rheumatology and Clinical Immunology
Experimentelle Rheumatologie
c/o Dt. Rheuma-Forschungszentrum
Charitéplatz 1
D-10117 Berlin
Phone: +49 30 28460-665
Fax: +49 30 28460-656
E-Mail: hamann@drfz.de
Duration: 01/05 - 12/16
Homepage: http://www.sfb650.charite.de/
CRC 665: Developmental disturbances in the nervous system
Progress in genetics and microbiology within the past twenty years has made it possible to analyze molecules that control the development of the central nervous system. Researchers can now identify genetic changes which lead to the formation of developmental disorders. However, the mechanisms or molecules that form and maintain neural circuits have not yet been fully investigated, and this is the challenge for both basic and clinical neuroscience researchers working in this Collaborative Research Centre.
Spokesperson:
Prof. Dr. Christian Rosenmund
Neuroscience Research Center (NWFZ) Charité - Universitätsmedizin Berlin
Charitéplatz 1
D-10115 Berlin
Tel.: +49 30 450-539 061
Fax: +49 30 450-570 936
E-Mail: sfb@665.charite.de
Duration: 07/05 - 06/17
Homepage: http://www.charite.de/sfb665/
CRC 740: From molecules to modules: organization and dynamics of functional cellular units
Functional modules are in the focus of the investigations. A functional module is considered to be an ensemble of macromolecules (proteins or RNA) which has a specific, largely autonomous function in biological cells. Among the functional modules there are macromolecular machines like ribosomes and proteasomes as well as unstable, dynamically organized protein ensembles similar to those found in intracellular transport.
Spokesperson:
Prof. Dr. Christian Spahn
Charité - Universitätsmedizin Berlin
Institute of Medical Physics and Biophysics
Ziegelstr. 5-9
D-10117 Berlin
Phone: +49 30 450-524131
Fax: +49 30 450-524931
E-Mail: chistian.spahn@charite.de
Duration: 01/07 - 12/18
Homepage: http://www.sfb740.de/
CRC 760: Biomechanics and biology of musculoskeletal regeneration
Spokesperson:
Prof. Dr. Georg Duda
Charité - Universitätsmedizin Berlin
Center for Musculoskeletal Surgery
Clinic for Trauma and Reconstructive Surgery
Augustenburger Platz 1
D-13353 Berlin
Phone: +49 30 450-559079
Fax: +49 30 450-559969
E-Mail: georg.duda@charite.de
Duration: 01/07 - 12/10
CRC 951: Organic/anorganic hybrid systems (HIOS)
Artificial hybrid materials consisting of semi-conductors, conjugated organic molecules and metallic nano-structures are in the centre of this research. As a result of the interaction of these very different components, new chemical and physical properties come into being, which need to be understood, controlled and utilized in order to be able to carry out increasingly complex opto-electronic functions in minute spaces.
Spokesperson:
Prof. Dr. Norbert Koch
Humboldt Universität zu Berlin
Department of Physics
Brook-Taylor-Straße 6
D-12489 Berlin
Phone: +49 30 2093-7819
Fax: +49 30 2093-7443
E-Mail: e-Mail
Duration: 07/11 - 06/23
CRC 1109: Understanding of Metal Oxide / Water Systems at the Molecular Scale: Structural Evolution, Interfaces, and Dissolution.
The research aims at a comprehensive understanding of the complex atomic scale processes underlying oxide formation, structural evolution and dissolution. Exemplarily, silica, alumina and iron oxides will be studied as metal oxides with the highest natural abundance and application relevance. In the long term the research results will be useful to reach a rational synthesis of oxides with desirable properties, such as stability towards corrosion.
Spokesperson:
Prof. Dr. Christian Limberg
Faculty of Mathematics and Natural Sciences
Department of Chemistry
Brook-Taylor Str. 2
D-12489 Berlin
Tel.: +49 30 2093-7382
Fax: +49 30 2093-6966
E-Mail: christian.limberg@chemie.hu-berlin.de
Duration: 04/14 - 12/17
CRC/TR 43: The brain as a target of inflammatory processes (Transregio)
Immunological processes are of singnificance not only in "classical" inflammatory diseases of the nervous system, as for example multiple sclerosis. They are fairly common also in primarily non-inflammatory conditions such as strokes, cerebral tumors and neuro-degenerative illnesses. Research within the framework of this project aims to investigate and find out joint cellular and molecular mechanisms and to develop new therapies.
Spokesperson:
Prof. Dr. Frank Heppner
Charité - Universitätsmedizin Berlin
Institute of Neuropathology
Charitéplatz 1
D-10117 Berlin
Phone: +49 30 450-536042
Fax: +49 30 450-536940
E-Mail: frank.heppner@charite.de
Duration: 01/08 - 12/16
Homepage: http://www.charite.de/sfb-trr43
CRC/TR 54: Growth and survival, plasticity and cellular interactivity of lymphatic neoplasies (Transregio)
Research within this project is concerned with the investigation of cellular processes going on at the onset and during the spreading of malignant diseases of immune cells (lymphomas). It is generally understood that fundamental principles of tumour formation valid in cases of lymphoma will also be relevant to other types of cancer. The research results are to contribute to novel therapies of cancer.
Spokesperson:
Prof. Dr. med. Clemens A. Schmitt
Charité - Universitätsmedizin Berlin
Internal Medicine Clinic, Specializing in Haematology and Oncology
Augustenburger Platz 1
D-13353 Berlin
Phone: +49 30 450-553 896
Fax: +49 30 450-565 976
E-Mail: clemens.schmitt@charite.de
Duration: 01/08 - 12/12
CRC/TR 84: Congenital immunity of the lung: mechanisms of pathogenic attacks and host defence in pneumonia
Pneumonia is a very common disease. 12 to 14 per cent of the patients who are hosptilized with the condition die eventually although they were given adequate amounts of antibiotics. In the framework of this project researchers investigate how bacteria and viruses cause damage to the lung and how the lung reacts to eliminate the pathogens. The researchers involved aim to contribute to new approaches to the therapy of pneumonia, which in addition to antibiotics will reduce the high pneumonia mortality rates.
Spokesperson:
Prof. Dr. Norbert Suttorp
Charité - Universitätsmedizin Berlin
Internal Medicine Clinic, Specializing in Infectiology
Augustenburger Platz 1
D-13353 Berlin
Phone: +49 30 450-553052
Fax: +49 30 450-553906
E-Mail: Norbert.Suttorp@charite.de
Duration: 07/10 - 06/18
Homepage: http://www.sfb-tr84.de